Complete Technical & Buyer's Guide

PSA Medical Oxygen Generator
for Hospitals

Everything you need to understand, specify, and procure a PSA oxygen generation system for your healthcare facility — from a manufacturer with 45 years of global experience.

1

Compression

Ambient air compressed by oil-free compressor. 21% O₂, 78% N₂.

2

Adsorption

Zeolite molecular sieve captures nitrogen. Oxygen passes through.

3

Delivery

Oxygen stored in buffer tank, delivered to hospital pipeline 24/7.

95%
O₂ Purity
24/7
Continuous Supply
4 bar
Delivery Pressure
100%
Supply Independence
80+
Countries with active projects
45+
Years manufacturing experience
95%
Oxygen purity — exceeds Ph.Eur.
70%
Average savings vs. cylinder supply
The Technology
How PSA oxygen
generation works

Pressure Swing Adsorption is a proven process that produces medical-grade oxygen continuously from ambient air — with no external supply chain required.

1

Air Compression

An oil-free compressor draws in ambient air and compresses it to the operating pressure required for the adsorption process. Oil-free operation is a non-negotiable requirement — any oil contamination of the medical oxygen stream is a serious clinical hazard.

2

Nitrogen Adsorption

Compressed air passes through twin vessels filled with zeolite molecular sieve — a highly porous material that selectively adsorbs nitrogen while allowing oxygen to pass through. As one vessel adsorbs, the other regenerates simultaneously, creating continuous uninterrupted flow.

3

Storage and Pipeline Delivery

The oxygen-enriched gas — at up to 95% purity — is collected in a buffer tank before delivery to the hospital pipeline at the required pressure (typically 4 bar). Continuous monitoring detects any deviation from specification and triggers automatic failover.

4

Fully Automatic Operation

Modern PSA systems like ULTRAOX® operate entirely automatically via PLC control. No operator required for normal function. The system monitors itself, manages the swing cycle, logs alarms, and can be monitored remotely.

O₂
Output purityUp to 95%
Why Hospitals Are Switching
Four reasons the world
is moving to on-site generation
Supply chain independence

Every hospital dependent on cylinder or liquid oxygen delivery is exposed to supplier delays and transport disruptions. During COVID-19, hospitals in dozens of countries ran out of oxygen — not because oxygen didn't exist, but because supply chains couldn't scale. Facilities with on-site PSA generators continued operating without interruption.

70%
Average cost reduction vs. cylinder supply over 5 years
Continuous, uninterrupted supply

PSA systems operate 24/7/365, matched to real-time demand. No end-of-cycle shortfalls, no weekend gaps, no emergency orders.

Significant long-term savings

Capital investment is typically recovered within 12–36 months. Over a 10-year lifespan, savings frequently exceed 70% of equivalent cylinder supply cost.

WHO-aligned and procurement-compliant

The WHO recognises PSA generation as an appropriate method for producing medical oxygen. Certified PSA systems satisfy most international procurement frameworks including UN agency tenders.

Supply Method Comparison
PSA vs. Liquid Oxygen
vs. Cylinders

No single method suits every facility. Here is an objective comparison across the factors that matter most to procurement and clinical teams.

FactorCylinder OxygenLiquid Oxygen (LOX)PSA On-Site Generation
Capital investmentLowMediumMedium–High
Running costHighMediumLow (electricity only)
Supply chain dependencyHighHighNone
Remote / rural suitabilityModeratePoorExcellent
5-year total cost of ownershipHighestMediumLowest
Payback periodN/AN/A12–36 months
WHO recommendedYesYesYes
Best suited forSmall clinics, backup supplyLarge urban hospitals with reliable logisticsMedium–large hospitals, remote facilities, national programmes
Sizing Your System
How to size a PSA
system for your hospital

Correct sizing is critical. A system sized only for average demand will fail during peak events. These are the factors that determine the right system for your facility.

Peak flow rate — not average

Size for peak simultaneous demand: ICU, theatres, and emergency running concurrently. Undersizing will leave you short when it matters most.

Bed count and clinical mix

ICU and surgical beds consume significantly more oxygen per hour than general ward beds. Provide the total bed count and clinical mix for an accurate spec.

Pipeline pressure requirements

Hospital medical gas pipelines typically operate at 4 bar. Verify your facility's pressure specification before sizing the output stage.

Redundancy and backup requirements

Regulatory requirements often mandate a backup oxygen source. Duplexed systems or a cylinder manifold backup should be included in the specification.

Growth projections

A system sized only for current demand may be insufficient within 3–5 years. Modular PSA systems — where capacity can be added as demand grows — are preferable for expanding facilities.

Procurement Checklist
What to look for when
choosing a PSA supplier

Not all PSA oxygen generators are equivalent. These are the non-negotiable criteria that every procurement team should verify before awarding a contract.

01

CE Medical Device Certification

A PSA medical oxygen generator must be certified as a medical device under the applicable EU directive. Systems without this certification are not legally compliant for hospital use in most jurisdictions. ULTRAOX® was the first PSA system certified as a medical device under the European Directive.

02

ISO 13485 Manufacturer Certification

This standard governs the quality management system of the manufacturer — not just the product. ISO 13485 means the design, production, and post-market surveillance processes meet international medical device standards.

03

Oxygen Purity ≥ 93% (Ph.Eur./USP)

Both the European Pharmacopoeia and the US Pharmacopeia specify a minimum purity of 93% (±3%) for PSA-produced medical oxygen. Verify that the system's specification explicitly cites pharmacopoeia compliance.

04

Oil-Free Compressor

The compressor feeding the PSA process must be oil-free. This is not optional. Any oil contamination of the medical oxygen stream presents a direct clinical hazard to patients.

05

Continuous Gas Monitoring

The system should continuously monitor O₂ concentration, CO, CO₂, water vapour, and trace gases. Any deviation should trigger automatic alarm and failover to the backup supply.

06

After-Sales and Spare Parts Commitment

A PSA generator is a 15–20 year investment. Verify that the supplier has a defined maintenance programme, genuine spare parts availability, and a technical support commitment — not just a warranty card.

ULTRAOX®
The next generation of
medical oxygen.

ULTRAOX® is Ultra Controlo's flagship PSA medical oxygen generator — designed and manufactured in Portugal, deployed in hospitals and health facilities across more than 80 countries since 1981.

CE 1639 — First PSA system certified as a medical device under European Directive 93/42/EEC
ISO 13485:2016 — Medical quality management system, renewed and current
Oil-free compressor — contaminant-free oxygen stream, guaranteed
Fully automatic PLC — continuous monitoring, automatic failover, remote diagnostics
Container option available — for remote, infrastructure-limited, or rapid-deployment environments
95%
Maximum O₂ purity — exceeds European and American Pharmacopoeia parameters
80+
Countries with active ULTRAOX® installations
24/7
UltraCare international technical support
45+
Years manufacturing medical gas systems in Portugal
3
Configurations: SC (indoor), ST (outdoor), CO (container)

Frequently asked questions

Can PSA oxygen be used for all clinical applications, including ICU and surgery?

Yes. PSA-generated oxygen meeting pharmacopoeia purity standards (minimum 93% O₂) is clinically equivalent to cylinder or liquid oxygen and is appropriate for all hospital applications, including mechanical ventilation, anaesthesia, neonatal care, and hyperbaric oxygen therapy. This position is supported by the WHO and major international health authorities.

How long does installation take?

A straightforward indoor installation can typically be commissioned within 2 to 4 weeks of equipment arrival on site. Containerised systems (ULTRAOX CO) can be operational faster, as they arrive pre-assembled and require only utility connections. Ultra Controlo's team manages the complete installation and commissioning process, including staff training.

What are the electricity requirements?

Power consumption depends on the system's production capacity. A system producing 20 Nm³/hour of oxygen typically consumes approximately 7 to 10 kW. Ultra Controlo's engineering team will provide a precise power specification during the site assessment phase.

What maintenance does a PSA system require?

A well-designed PSA system requires periodic preventive maintenance — typically every 6 to 12 months — covering filter replacement, zeolite sieve inspection, compressor servicing, and monitoring system calibration. Ultra Controlo's UltraCare programme provides scheduled maintenance with 24/7 emergency support.

Is PSA oxygen approved by the WHO?

Yes. The WHO specifically recommends on-site PSA oxygen generation as an appropriate method for producing medical oxygen in healthcare facilities, particularly in low- and middle-income countries. PSA-generated oxygen is listed in the WHO Essential Medicines framework.

Can ULTRAOX® operate in hot, remote, or challenging environments?

Yes. The containerised ULTRAOX CO system is engineered for extreme environments — including desert, tropical, high-altitude, and island locations. Systems are currently operational in the Sahara, the Amazon, islands in the Pacific, and high-altitude sites in the Andes.

Ready to discuss your
oxygen system requirements?

Our engineering team provides free project assessments, system sizing, and technical support throughout the procurement process.

ISO 13485 Certified
CE 1639 Medical Device
80+ Countries
45+ Years Experience
24/7 UltraCare Support